Molecular Genetics of Prokaryotes

The operon model was proposed by Jacob, Monod, and Wollman based on studies on lactose-requiring mutations of E. coli. In this problem set you will work with the types of genetic and biochemical information used to unravel the inner workings of the lac operator-repressor regulation system.

Instructions: The following problems have multiple choice answers. Correct answers are reinforced with a brief explanation. Incorrect answers are linked to tutorials to help solve the problem.
  1. Components of the lac operon of E. coli
  2. The role of the inducer of the lac operon
  3. Phenotype of lac Z- E. coli cells
  4. Exchange of genetic information between bacteria
  5. DNA transfer by an F factor
  6. Different alleles for a bacterial genes
  7. Regulation of lac Z gene on an F' episome
  8. The Oc mutation of the lac operon
  9. Phenotype of lac I- cells
  10. Phenotype of cells diploid for lac I gene
  11. The effect of high glucose on lac operon expression
  12. Effect of high glucose concentrations
  13. Effect of high lactose and low glucose on lac operon
  14. Effect of the absence of glucose

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Updated: July 15, 1999
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