Acids & Bases Problem Set

Question 10: Relationship between pK_a and pH

The correct operational relationship between pK_a and pH is that:

A.	both are log functions.
B.	both are always <7 for acids, and >7 for bases.
C.	These two concepts are not operationally related in any way since biological fluids contains mixtures of too many acids and bases.
D.	When pH = pKa , the compound in question will have a charge of +0.5.
E.	When pH = pKa , the ionizable compound in question (whether acid or base) will be half protonated and half deprotonated. This is in fact the very definition of pKa.