Eukaryotic Gene Expression Problem Set

Problem 1: Post transcriptional modification to the 3'-end of eukaryotic mRNAs

Correct!

What is added to the 3'-end of many eukaryotic mRNAs after transcription?

A. introns

B. a poly A tail
A tail of A-nucleotides, generally 100-200 long, is added to the 3'-end of most eukaryotic pre-mRNAs. The poly A tail, which is not coded in the DNA, is also retained in the mRNA exported to the cytoplasm.

C. a cap structure, consisting of a modified G nucleotide

D. the trinucleotide 5'-CCA

E. exons

The Biology Project
University of Arizona
Monday, October 27, 1997
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