Tutorial to help answer the question
Which HIV+ patient is most likely to have AIDS?
A. |
A person who engaged in high-risk sexual behavior three months
ago |
B. |
A person who engaged in high-risk sexual behavior ten years
ago |
C. |
A recently infected person whose drug therapies include reverse
transcription inhibitors and protease inhibitors |
D. |
A person who has an almost normal number of helper T cells
detected in her blood sample |
Tutorial
AIDS (acquired immunodeficiency syndrome) is caused by HIV infection.
HIV infects helper T cells, specialized white blood cells which regulate the body's antigen-specific
immune response. These vital cells are killed by HIV infection,
and by cytotoxic T cells which kill infected helper T cells. Although
initially the body can replace damaged helper T cells, over years,
the helper T cell population is eventually depleted. When too many
helper T cells are lost, the body can no longer launch a specific
immune response and becomes susceptible to many opportunistic infections.
HIV+ individuals are considered to have AIDS when their helper T
cell counts below 200 cells/mm3 and they suffer from
opportunistic infections.
Today drug therapies including reverse transcription inhibitors
and protease inhibitors can greatly reduce the progression of HIV
infection. HIV+ individuals receiving treatment can live many years
without suffering from AIDS.
|