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Carbohydrate Metabolism Regulation Problem Set

In this module, you will learn about how certain carbohydrate pathways are reciprocally affected by insulin and glucagon. The areas of focus will be:

a) regulation of glycolysis by phosphorylation/dephosphorylation of key enzymes;
b) regulation of glycogen formation vs. breakdown, again by phosphorylation/dephosphorylation;
c) how this regulation is coordinated so as to avoid futile cycling and trapping of intermediates;
d) how this regulation fits with the overall function of insulin vs. glucagon.

Instructions: The following problems have multiple choice answers. Correct answers are reinforced with a brief explanation. Incorrect answers are linked to tutorials to help solve the problem.
    1. Liver enzymes affected by insulin
    2. Enzyme dephosphorylation by insulin action
    3. PFK-1 regulation in liver
    4. Insulin regulation of glucokinase
    5. Enzyme phosphorylation induced by glucagon
    6. Epinephrine action to mobilize glycogen
    7. A secondary action of epinephrine in liver
    8. Insulin action in skeletal muscle

Problem 1

Vocabulary | Credits

The Biology Project Home > Biochemistry > Regulation of Carbohydrate Metabolism > Problem Set
The Biology Project
The University of Arizona
March 16, 2001
Revised: August, 2004
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