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Hydroxyl Amino Acids

Hydroxyl amino acids are polar, uncharged at physiological pH, and hydrophilic. The phenolic hydroxyl ionizes with a pKa of 10 to yield the phenolate anion. The hydroxyl groups of serine and threonine are so high that they are generally regarded as nonionizing.

Molecular Structure for Serine HO-CH2-CH(NH3)-COO molecular structure of threonine CH3-CH(OH)-CH(NH3)-COO Molecular Structure of Tyrosine HO-p-Ph-CH2-CH(NH3)-COO
Chemical structure for serine   Chemical structure for threonine    Chemical structure of tyrosine

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The Biology Project > Biochemistry > The Chemistry of Amino Acids

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Department of Biochemistry and Molecular Biophysics
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August 25, 2003
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