A.
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The frequency increases dramatically in mothers over the age
of 40.
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B.
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The cause is a nondisjunction when chromosomes do not
separate during the first meiotic division.
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C.
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Affected individuals have an extra autosome.
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D.
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The long time lag between onset of meiosis in ovarian tissue
(during fetal development) and its completion (at ovulation) is most
likely the reason for increased incidence in older mothers.
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E.
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None, all statements are true.
Down's syndrome is also known as trisomy 21.
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