Introduction to Immunology
Problem 13. Monoclonal antibodies
Within the body, a B cell with a specific antibody can undergo clonal expansion (make many copies of itself) in the absence of antigen.
B cells can only proliferate and
make a strong immune response if helper T cells give activation
signals. Without the helper T cells, B cells can response
only to a limited number of antigens, usually those with
repeating structures such as a bacterial cell wall polysaccharide.
13 | Tutorial
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