The Biology Project: Immunology

Introduction to Immunology

Problem 5. Antibody diversity


The ability to produce billions of different antibodies in humans results from:

A. The presence of billions of complete antibody genes in B cells
B. The fact that both T cells and B cells contain antibody genes

The production of variable regions of light and heavy antibody genes by DNA rearrangement

The combination of gene fragments prior to binding antigen produces the variable coding sequence for the antibody gene.
D. The fact that a single antibody gene produces an antibody capable of billions of different three-dimensional structures and the ability to combine with any antigen


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