DNA Forensics Problem Set 1

The purpose of this problem set is to present an introduction to the use of the Restriction Fragment Length Polymorphism (RFLP) method to characterize human DNA samples as applied in paternity analysis and sex crimes investigations. You will have the opportunity to interpret actual case results as might be produced by the FBI laboratory or a commercial, paternity-testing facility.

Instructions: The following problems have multiple choice answers. Correct answers are reinforced with a brief explanation. Incorrect answers are linked to tutorials to help solve the problem.
  1. Southern hybridization technique
  2. Determining paternity
  3. Father's profile
  4. Rape investigation
  5. VNTR: hypervariable regions
  6. Probability

The Biology Project
University of Arizona
Revised: September 2000
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